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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
23.03
Human Site:
S188
Identified Species:
50.67
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
S188
I
S
S
S
M
D
I
S
G
T
K
C
D
F
T
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S303
I
S
S
S
M
D
I
S
G
T
K
C
D
F
T
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
D184
D
I
S
G
T
K
C
D
F
T
V
Q
V
Q
L
Dog
Lupus familis
XP_535524
651
71773
S188
I
S
S
S
M
D
I
S
G
T
K
C
D
F
T
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
S188
I
S
S
S
M
D
I
S
G
T
K
C
D
F
T
Rat
Rattus norvegicus
O70260
628
68345
Q170
A
L
T
P
Q
Q
L
Q
Q
I
L
T
S
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
S287
I
S
S
S
M
D
I
S
G
T
K
C
D
F
T
Chicken
Gallus gallus
NP_001026627
564
62782
S106
Y
D
G
H
P
A
T
S
P
L
L
P
V
S
L
Frog
Xenopus laevis
NP_001079161
649
71676
S187
I
S
S
S
M
D
I
S
G
T
K
C
D
F
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
A280
I
S
K
I
S
Y
R
A
D
V
T
P
L
P
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
D194
T
A
T
T
I
P
N
D
G
A
S
T
M
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
0
N.A.
100
6.6
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
100
6.6
100
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
55
0
0
0
% C
% Asp:
10
10
0
0
0
55
0
19
10
0
0
0
55
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
55
0
% F
% Gly:
0
0
10
10
0
0
0
0
64
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
64
10
0
10
10
0
55
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
0
55
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
10
0
0
10
19
0
10
0
19
% L
% Met:
0
0
0
0
55
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
10
0
0
10
0
0
19
0
10
0
% P
% Gln:
0
0
0
0
10
10
0
10
10
0
0
10
0
19
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% R
% Ser:
0
64
64
55
10
0
0
64
0
0
10
0
10
10
10
% S
% Thr:
10
0
19
10
10
0
10
0
0
64
10
19
0
0
55
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _